Research Article

Skeletal Effects of the Saturated 3-Thia Fatty Acid Tetradecylthioacetic Acid in Rats

Table 2

Histomorphometric analysis of trabecular bone volume, total, cortical, and medullary area in distal femur after four months of treatment with TTA (Study I).

Group CTR
(controls given vehicle) ( 𝑁 = 1 2 )
TTA
(given TTA) ( 𝑁 = 1 2 )

Trabecular bone volume (%) 2 2 . 2 ± 5 . 9 5 2 2 . 1 ± 4 . 7 0
Total area (mm2) 6 . 2 6 ± 0 . 3 2 6 . 6 5 ± 0 . 3 2 a
Cortical area (mm2) 3 . 9 9 ± 0 . 2 9 4 . 2 7 ± 0 . 2 4 a
Medullary area (mm2) 2 . 3 5 ± 0 . 2 5 2 . 3 7 ± 0 . 1 5

Data are presented as mean ± SD, a 𝑃 < 0 . 0 5 significantly different compared to control.