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PPAR Research
Volume 2011 (2011), Article ID 523520, 8 pages
http://dx.doi.org/10.1155/2011/523520
Research Article

PPAR-α Agonist Fenofibrate Upregulates Tetrahydrobiopterin Level through Increasing the Expression of Guanosine 5′-Triphosphate Cyclohydrolase-I in Human Umbilical Vein Endothelial Cells

1Department of Endocrinology, Peking University Third Hospital, Beijing 100191, China
2Department of Cardiology, Beijing Tongren Hospital, Beijing 100191, China
3Department of Physiology and Pathophysiology, School of Basic Medical Sciences and Key Laboratory of Molecular Cardiovascular Science of Ministry of Education, Peking University Health Science Center, Beijing 100191, China
4Department of Cardiovascular Medicine, Peking University Third Hospital, Beijing 100191, China
5Department of Surgery, University of Pittsburgh School of Medicine and Vascular Surgery Research, Pittsburgh, PA 15240, USA

Received 10 June 2011; Revised 4 August 2011; Accepted 4 September 2011

Academic Editor: Nanping Wang

Copyright © 2011 Jinbo Liu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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