Research Article

Rosiglitazone Affects Nitric Oxide Synthases and Improves Renal Outcome in a Rat Model of Severe Ischemia/Reperfusion Injury

Figure 5

Effect of 5 mg/kg rosiglitazone (RGZ) on the relative expression of cleaved caspase 3 (CC3) in renal cortex of Sprague-Dawley rats in renal I/R injury. Antibody against CC3 recognized a band in the range of 18 kDa; the anti-β-actin antibody recognized a band at 42 kDa. The amount of CC3 Western blot against CC3 and β-actin was performed as described in Section 2. Western blot signal was normalized to the respective signal from β-actin. *Statistically significant difference with ; n as indicated.
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