PPAR Research / 2012 / Article / Fig 6

Research Article

Rosiglitazone Affects Nitric Oxide Synthases and Improves Renal Outcome in a Rat Model of Severe Ischemia/Reperfusion Injury

Figure 6

Effect of 5 mg/kg rosiglitazone (RGZ) on invasion of ED-1-positive cells (monocytes/macrophages) in renal cortex of Sprague-Dawley rats in renal I/R injury. (a) ED-1-positive cells were detected in renal cryostat sections by immunofluorescence as described in Section 2. (a) Macrophage/monocyte invasion is given as the amount of ED-1-positive cells per visual field. n as indicated. * and # indicate statistically significant difference with . (b) Representative immunohistochemistry images of the renal cortex (magnification 1 : 10) after ED1 staining are depicted. Respective groups as indicated on the sections.

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