The Effect of PPAR Agonists on the Migration of Mature and Immature Eosinophils

Table 1

Eosinophil expression of CCR3 and phosphorylation of ERK1/2 and p38 after treatment with the PPARγ agonist rosiglitazone.

		Diluent	0.1 nM	10 nM	𝑃 value
CCR3 (%)		29.3±7.5	23.5±5.7	19.8±4.7	0.1
CCR3 (MFI)		8.3±4.4	6.8±3.3	5.4±2.8	0.2
Phospho-ERK1/2 (units/mL)	Diluent	3.5±0.7	3.3±0.6	3.3±0.5	0.6
	Eotaxin	3.75±0.2	3.93±0.4	3.95±0.4	0.8
Phospho-p38 (units/mL)	Diluent	3.9±1	4.8±1.3	4.5±1.8	0.9
	Eotaxin	6.7±1.9	6.2±1.5	7.0±1.4	0.8

Data represent mean + SEM.