Protective Effects of Peroxisome Proliferator-Activated Receptor-<i>α</i> Agonist, Wy14643, on Hypoxia/Reoxygenation Injury in Primary Rat Hepatocytes

<table>The content of ROS in different groups was determined by DCFH-DA (Mean ± SD, <svg height="11.225" id="M71" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 36.237499 11.225" width="36.237499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,10.963)"><use xlink:href="#x1D45B"></use></g><g transform="matrix(.017,-0,0,-.017,13.305,10.963)"><use xlink:href="#x3D"></use></g><g transform="matrix(.017,-0,0,-.017,28.008,10.963)"><use xlink:href="#x36"></use></g>
</svg>). After 4 h of hepatocellular hypoxia and 10 h of reoxygenation. <svg height="17.7125" id="M72" style="vertical-align:-3.276pt" version="1.1" viewbox="0 0 67.199997 17.7125" width="67.199997" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.012,-0,0,-.012,2.9,5.4)"><use xlink:href="#x63"></use></g>
<g transform="matrix(.017,-0,0,-.017,8.55,14.75)"><use xlink:href="#x1D443"></use></g><g transform="matrix(.017,-0,0,-.017,24.088,13.563)"><use xlink:href="#x3C"></use></g><g transform="matrix(.017,-0,0,-.017,38.774,13.563)"><use xlink:href="#x30"></use></g><g transform="matrix(.017,-0,0,-.017,46.934,13.563)"><use xlink:href="#x2E"></use></g><g transform="matrix(.017,-0,0,-.017,50.81,13.563)"><use xlink:href="#x30"></use></g><g transform="matrix(.017,-0,0,-.017,58.969,13.563)"><use xlink:href="#x31"></use></g>
</svg> versus control group;  <svg height="20.8375" id="M73" style="vertical-align:-3.276pt" version="1.1" viewbox="0 0 65.6875 20.8375" width="65.6875" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.012,-0,0,-.012,2.9,8.537)"><use xlink:href="#x66"></use></g>
<g transform="matrix(.017,-0,0,-.017,7.037,17.888)"><use xlink:href="#x1D443"></use></g><g transform="matrix(.017,-0,0,-.017,22.575,16.7)"><use xlink:href="#x3C"></use></g><g transform="matrix(.017,-0,0,-.017,37.262,16.7)"><use xlink:href="#x30"></use></g><g transform="matrix(.017,-0,0,-.017,45.421,16.7)"><use xlink:href="#x2E"></use></g><g transform="matrix(.017,-0,0,-.017,49.297,16.7)"><use xlink:href="#x30"></use></g><g transform="matrix(.017,-0,0,-.017,57.456,16.7)"><use xlink:href="#x31"></use></g>
</svg> versus H/R group.</table>

PPAR Research

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Figure 3

Figure 3: Protective Effects of Peroxisome Proliferator-Activated Receptor-<i>α</i> Agonist, Wy14643, on Hypoxia/Reoxygenation Injury in Primary Rat Hepatocytes 

Figure 3 | Protective Effects of Peroxisome Proliferator-Activated Receptor-α Agonist, Wy14643, on Hypoxia/Reoxygenation Injury in Primary Rat Hepatocytes 