PPARγ in Inflammatory Bowel Disease

Table 3

Efficacy of rosiglitazone therapy in ulcerative colitis (^∗𝑃 values < 0.05).

Authors	N° pts	Study design	Treatment	% Efficacy
				Response	Remission	Mucosal healing
Lewis et al. 2001 [68]	15	Open 12 weeks	4 mg tid	—	27	20
Liang and Ouyang 2006 [69]	42	Random versus 5-ASA	4 mg	—	71 versus 57*	—
Lewis et al. 2008 [70]	105	12 wks versus Plac	4 mg tid	44 versus 23*	17 versus 2*	8 versus 2
Pederson and Brynskov 2010 [71]	14	Open versus 5-ASA	4 mg versus 1 enema	= 5-ASA	= 5-ASA	—