Peroxisome Proliferator Activated Receptor-α Agonist Slows the Progression of Hypertension, Attenuates Plasma
Interleukin-6 Levels and Renal Inflammatory Markers in Angiotensin
II Infused Mice
Figure 2
Mean arterial pressure of PPAR-α KO mice [18] (•) and PPAR-α WT mice [9] (o) during control days 1–7, days 1–3 of fenofibrate treatment, and days 1–12 of Ang II + fenofibrate treatment. MAP was significantly higher in KO + Ang II + Fen versus WT + Ang II + Fen (*).