PPAR Research / 2012 / Article / Fig 2

Review Article

Regulation of Genes Involved in Carnitine Homeostasis by PPARα across Different Species (Rat, Mouse, Pig, Cattle, Chicken, and Human)

Figure 2

Sequence alignment of the functional PPRE in the promoters, intron 1 and intron 2, respectively, of human, mouse, rat, pig, cattle, and chicken BBOX1. The PPRE, which is comprised of two hexanucleotides separated by a single nucleotide, termed direct repeat 1, is underlined. Matching nucleotides are shown by asterisks. The BBOX1-PPRE for S. scrofa is not shown due to gaps in the first and second intron. Chromosomal localization, accession number of cDNA, and genomic DNA sequences from Genbank of NCBI are: hBBOX1 chr.11, NM_003986 cDNA, AC015756 genomic DNA; mBBOX1 chr.2, NM_130452 cDNA, AL691416 genomic DNA; rBBOX1 chr.3, NM_022629/FQ210746 cDNA, AABR03024937 genomic DNA; cBBOX1 chr.15, NM_001101881 cDNA, genomic DNA; sBBOX1 chr.2, AK393528/AK391112 cDNA. CU694591 genomic DNA; chBBOX1 Chr.5, BX936048 cDNA, JH374511 genomic DNA.

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