Peroxisome Proliferator-Activated Receptor α Plays an Important Role in the Expression of Monocyte Chemoattractant Protein-1 and Neointimal Hyperplasia after Vascular Injury
Figure 3
Photomicrographs of CD45 immunostaining showing injured carotid arteries from PPARα knockout mouse, WT mouse, and WT mouse treated with Wy14643 at day 4 after injury (63x). (A) Representative cross-section of CD45 expression from PPARα knockout group. (B) Representative cross-section of CD45 expression from WT group. (C) Representative cross-section of CD45 expression from WT treated with Wy14643 group. More extensive CD45 expression was observed in PPARα knockout mouse when compared to WT mouse. The treatment with Wy14643 further decreased CD45 expression.