Peroxisome Proliferator-Activated Receptor α Plays an Important Role in the Expression of Monocyte Chemoattractant Protein-1 and Neointimal Hyperplasia after Vascular Injury

Table 1

Morphometric data at 21 days.

	PPAR𝛼^−/− (𝑛=11)	WT (𝑛=13)	WT with Wy14643 (𝑛=15)	PPAR𝛼^−/− with Wy14643 (𝑛=10)
Luminal area (mm^2)	0.068 ± 0.019	0.088 ± 0.018	0.086 ± 0.021	0.069 ± 0.014
Neointimal area (IA, mm^2)	0.020 ± 0.009^*	0.009 ± 0.005^§	0.005 ± 0.003	0.021 ± 0.007^*
Medial area (MA, mm^2)	0.033 ± 0.004	0.026 ± 0.011	0.030 ± 0.017	0.030 ± 0.012
EEL area (mm^2)	0.122 ± 0.024	0.123 ± 0.026	0.122 ± 0.031	0.128 ± 0.021
IA/MA	0.610 ± 0.244^*	0.379 ± 0.231^§	0.204 ± 0.116	0.798 ± 0.219^*

EEL: external elastic lamina.
^∗𝑃<0.05 when compared to both WT without and WT with Wy14643 groups.
^§𝑃<0.05 when compared to both PPAR𝛼^−/− and WT with Wy14643 groups.