Figure 4: Whole body turnover and tissue specific utilization rates of glucose and FFA. Glucose and FFA flux data are shown in the left and right hand panels, respectively, under basal (open histograms) and hyperinsulinemic clamp (closed histograms) conditions. Mean ± SEM ( ). , , and versus Obese basal state. , insulin effect in Obese versus Lean (based on Clamp-Basal differences). , , and insulin effect in Tesaglitazar (Tesa) versus Obese (based on Clamp-Basal differences).