PPAR Research / 2013 / Article / Tab 6

Clinical Study

Dual PPAR α/γ Agonism Normalizes Lipoprotein Profile of Renal Dyslipidemia

Table 6

Glomerular filtration rate and serum creatinine at entry, after administration of 1 mg tesaglitazar for 6 weeks, and at followup 3 weeks after drug administration. Mean and standard deviation (in parenthesis).

CKD patientsHealthy reference group
At entryAfter 6 weeksAfter 3 weeks of drugAt entryAfter 6 weeksAfter 3 weeks of drug

GFR (mL/min × 1.73 m2 BSA)43.2 (24.0)37.7 (21.1)43.4 (28.3)94.6 (13.2)91.9 (15.5)91.8 (10.4)
S-creatinine (µmol/L)201 (66)249 (93)226 (89)71 (11)79 (8)72 (10)