The Proatherogenic Effect of Chronic Nitric Oxide Synthesis Inhibition in ApoE-Null Mice Is Dependent on the Presence of PPARα
Figure 1
Lipoprotein FPLC analysis. Each curve represents the average of 4 samples, pooled from the sera of 2 mice each (error bars omitted for clarity). L-NAME increased VLDL cholesterol in the ApoE-null mice to the level seen in the DKO. DKO mice were not affected and maintained significantly higher LDL under all conditions ( for area under the curve, AUC).
