TRPV1 Activation Attenuates High-Salt Diet-Induced Cardiac Hypertrophy and Fibrosis through PPAR-δ Upregulation

Figure 6

Activation of TRPV1 relieves oxidative/nitrotyrosine stress in mice on long-term high-salt diet. (a) Representative examples of LV sections from WT and TRPV1^−/− mice stained for 3-nitrotyrosine. (b) 3-Nitrotyrosine staining and scoring of expression in LV of various groups. Values were expressed as the mean ± SEM from 7 separate experiments. ^∗∗𝑃<0.01 versus NS; ^##𝑃<0.01 versus HS.

(a)

(b)