TRPV1 Activation Attenuates High-Salt Diet-Induced Cardiac Hypertrophy and Fibrosis through PPAR-δ Upregulation
Activation of TRPV1 relieves oxidative/nitrotyrosine stress in mice on long-term high-salt diet. (a) Representative examples of LV sections from WT and TRPV1−/− mice stained for 3-nitrotyrosine. (b) 3-Nitrotyrosine staining and scoring of expression in LV of various groups. Values were expressed as the mean ± SEM from 7 separate experiments. versus NS; ## versus HS.