The Rate of Decline of Glomerular Filtration Rate May Not Be Associated with Polymorphism of the PPAR𝜸2 Gene in Patients with Type 1 Diabetes and Nephropathy

Table 1

Clinical characteristics and frequencies (%) of polymorphism of the PPAR𝛾2 gene in patients with type 1 diabetes and normal controls.

	Uncomplicated; (𝑛=81)	Nephropaths; (𝑛=116)	All patients; (𝑛=197)	Normal controls; (𝑛=151)
Male : Female	31 : 50	52 : 64	84 : 114	64 : 87
Age at onset of diabetes	17.1+11.0 (2–51)	15.2+9.3 (1–54)
Duration of diabetes	32.2+9.9 (20–65)	30.4+9.9 (13–65)
Genotype
Pro12Pro	65 (80.2)	90 (77.6)	155 (78.7)	125 (82.8)
Pro12Ala	14 (17.3)	25 (21.6)	39 (19.8)	23 (15.2)
Ala12Ala	2 (2.5)	1 (<1)	3 (1.5)	3 (2.0)
Allele
Pro12	144 (88.9)	205 (88.4)	349 (88.6)	273 (90.4)
Ala12	18 (11.1)	27 (11.6)	45 (11.4)	29 (9.6)