Smad2/3 Upregulates the Expression of Vimentin and Affects Its Distribution in DBP-Exposed Sertoli Cells

Figure 4

Immunofluorescence and immunocytochemical experiments of vimentin in control and DBP- and SB431542 + DBP-treated SCs at 24 h. (a) and (d) represent the control group; (b) and (e) represent the DBP-treated group; (c) and (f) represent the SB431542 + DBP-treated group (magnification: 200x). The distribution of vimentin showed abnormal aggregation in subregions of SCs (as shown by arrows) compared with the control group. The distribution of vimentin in the SB431542 + DBP-treated group showed many irregular long filamentous structures.

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