Review of the Structural and Dynamic Mechanisms of PPARγ Partial Agonism

Figure 4

Crystal structures of benzimidazole containing PPARγ partial agonists. (a) Poseview map of Compound 13. (b) Crystal structure of Compound 13 bound to the PPARγ ligand binding domain. PDB: 3S9S [52]. (c) Poseview map of Telmisartan. (d) Crystal structure of Telmisartan bound to the PPARγ ligand binding domain. PDB: 3VN2 [53]. The branches of the ligand binding pocket have been labelled with Roman numerals.

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