Testosterone Replacement Modulates Cardiac Metabolic Remodeling after Myocardial Infarction by Upregulating PPARα
Effects of castration and testosterone replacement on myocardial fibrosis and apoptosis. Representative magnification (200x) of Masson-Trichrome sections of the heart. (a) Cas+T+F group, (b) Cas+T group, (c) Cas group, (d) S-Cas group, (e) control group, and (f) quantitative analysis of fibrotic area. (g) The TUNEL-positive cells percent expressed as a percent of normal nuclei. Values are means ± SD; . S-Cas: sham-castration; Cas: castration; T: testosterone; F: flutamide. versus control group; , , and versus Cas.
Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.