Pioglitazone Attenuates Drug-Eluting Stent-Induced Proinflammatory State in Patients by Blocking Ubiquitination of PPAR

Figure 2

Pioglitazone downregulated the proinflammation in MNC. (a)–(c) Change in mRNA expression of peripheral blood mononuclear cells (MNC). The mRNA levels of IL-6, TNF-, and MMP-9 were detected by quantitative real-time PCR. (d) NF-κB DNA binding activity was detected. (e) The expression of p50 subunit and p65 subunit in MNC. and compared with baseline.

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