Research Article

Quercetin and Quercetin-Rich Red Onion Extract Alter Pgc-1α Promoter Methylation and Splice Variant Expression

Figure 3

Expressions of (a) FL-Pgc-1α, (b) Pgc-1α-a, (c) Pgc-1α-b, (d) Pgc-1α-c, (e) Pgc-1α4, and total NT-Pgc-1α isoforms were measured by qRT-PCR in skeletal muscle samples of mice fed a low fat (LF), high fat (HF), high fat plus quercetin (HF + Q), or high fat plus red onion extract (HF + RO) diet for 9 wks. Values are shown as means ± SEM in arbitrary units (AU). denotes significant difference with P < 0.05, P < 0.01, and P < 0.001.
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