Neuroprotective Effect and Mechanism of Thiazolidinedione on Dopaminergic Neurons In Vivo and In Vitro in Parkinson’s Disease

Figure 7

Effect of thiazolidinedione on apoptosis and levels of antiapoptosis proteins. (a) The expression of Bax, Bcl-2, and ERK in different groups; β-actin was used as the loading control. (b)–(e) express the protein levels of Bax, Bcl-2, and ERK. “a” indicates and “aa” indicates , compared with control group; “b” indicates and “bb” indicates , compared with MPP⁺ group; “c” indicates and “cc” indicates , compared with 0.01 μmol/L 2,4-TZD group; “d” indicates and “dd” indicates , compared with 0.1 μmol/L 2,4-TZD group.

(a)

(b)

(c)

(d)

(e)