Fimasartan Ameliorates Nonalcoholic Fatty Liver Disease through PPARδ Regulation in Hyperlipidemic and Hypertensive Conditions

Figure 1

Peroxisome proliferator-activated receptor delta (PPARδ), peroxisome proliferator-activated receptor alpha (PPARα), and peroxisome proliferator-activated receptor gamma (PPARγ) mRNA expression in HepG2 cells treated with high fatty acid and fimasartan. Total RNA was extracted from HepG2 cells treated with high fatty acid and fimasartan, and then complementary DNA (cDNA) was synthesized from the total RNA. PCR reactions for PPARδ, PPARα, and PPARγ were performed. The density of bands on agarose gel was analyzed with ImageJ program. The results are expressed as means ± SEM (). Values were statistically analyzed by unpaired t-test. All experiments were repeated three times.