Research Article
The Hepatoprotection by Oleanolic Acid Preconditioning: Focusing on PPARα Activation
Figure 5
OA regulates PPARα and JNK signaling in ConA-induced liver injury. Notes. (a) mRNA expression levels of PPARα and TRAF2 were measured with real-time PCR. (b) Protein expression levels of PPARα, TRAF2, total JNK, and phospho-JNK were determined using western blot. (c) Representative immunohistochemistry images (200x magnification) were used to evaluate the expression levels of PPARα, TRAF2, and phospho-JNK after 8 h of exposure to ConA (; for oil versus ConA; for ConA + OA (20 mg/kg) versus ConA; for ConA + OA (40 mg/kg) versus ConA; for ConA + OA (80 mg/kg) versus ConA).
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