Treatment of Diabetic Mice with a Combination of Ketogenic Diet and Aerobic Exercise via Modulations of PPARs Gene Programs

Figure 1

Ketogenic diet and ketogenic diet combined with exercise reduce body weights. (a) Changes in body weight during the 6-week treatment of ketogenic diet and aerobic exercise. Mice body weight of the diabetes + KD + AE group was significantly lower than that of the diabetes group, from the 5th week till the end. (b) Both ketogenic diet and a combination of aerobic exercise intervention could significantly decreased mice body weight. (c) Food intake and (d) water intake of diabetic mice were reduced after ketogenic diet or exercise. Data were presented as means ± SEM ( per group) and statistical analysis was performed with 1-way ANOVA. versus diabetic group.

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