Vascular Remodeling, Oxidative Stress, and Disrupted PPARγ Expression in Rats of Long-Term Hyperhomocysteinemia with Metabolic Disturbance

Figure 4

Representative images of stained heart sections. H&E stained sections from the control-diet group (a) and the Met-diet group (b) showed hyperhomocysteinemia induced coronary arteriolar wall thickening. Masson’s trichrome staining showed hyperhomocysteinemia induced collagen accumulation in coronary arterioles in the Met-diet group (d) compared with vessels from the control-diet group (c). The wall-to-lumen ratios of coronary arterioles in the Met-diet group were increased compared with the control-diet group () (e). Original magnification was ×100 for (a)–(d) and the scale bar = 100 um. Values are mean ± SEM.

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