Research Article

PPARγ Antagonizes Hypoxia-Induced Activation of Hepatic Stellate Cell through Cross Mediating PI3K/AKT and cGMP/PKG Signaling

Table 1

Grades of fibrosis in rat liver.

GroupsGrades
01234

Control55 (100%)0 (0%)0 (0%)0 (0%)0 (0%)
CCl4 + FiO2 (0.21)100 (0%)2 (20%)5 (50%)2 (20%)1 (10%
CCl4 + FiO2 (0.07)100 (0%)0 (0%)4 (40%)4 (40%)2 (20%
CCl4 + FiO2 (0.07) + RSG (10 mg/kg)100 (0%)7 (70%)3 (30%)0 (0%)0 (0%

as compared with control group. as compared with CCl4 + FiO2 (0.21) group. as compared with CCl4 + FiO2 (0.07) group.