Rosiglitazone, a Ligand to PPAR, Improves Blood Pressure and Vascular Function through Renin-Angiotensin System Regulation

Figure 7

Effect of rosiglitazone (RGZ) on total antioxidant capacity of sham or aortic coarctated (AoCo) rats treated with vehicle (V), rosiglitazone (5mg/kg, RGZ), or RGZ + bisphenol A diglycidyl ether (120 mg/kg, RGZ+BADGE). The parameter was evaluated in serum. The values represent the mean ± SEM (n=6 animals of group). One-way analysis of variance (ANOVA) post Tukey. ⁺P < 0.05 Sham-V vs. Sham-RGZ, ^∗P < 0.05 Sham-V vs. AoCo-V, ^#P < 0.05 AoCo-V vs. AoCo-RGZ, and ^&P < 0.05 AoCo-RGZ vs. AoCo-RGZ+BADGE.