Research Article
Activation and Expression of Peroxisome Proliferator-Activated Receptor Alpha Are Associated with Tumorigenesis in Colorectal Carcinoma
Table 2
The relationship of PPAR-
expression to clinicopathologic parameters of colorectal carcinoma (n=64).
| Parameters | Number of | PPAR-α | P-value | cases | (-) | (+) |
| Sex | | | | | | Male | 39 | 8 | 31 | 0.985 | | Female | 25 | 6 | 19 | Age | | | | | | ≤65 | 31 | 8 | 23 | 0.664 | | >65 | 33 | 6 | 27 | Histological type | | | | | | Well-to-moderately differentiated | 52 | 8 | 44 | 0.026 | | Mucinous | 12 | 6 | 6 | Lymphatic invasion | | | | | | Positive | 48 | 11 | 37 | 1.000 | | Negative | 16 | 3 | 13 | Venous invasion | | | | | | Positive | 48 | 10 | 38 | 1.000 | | Negative | 16 | 4 | 12 | Lymph node metastasis | | | | | | Positive | 21 | 5 | 16 | 1.000 | | Negative | 43 | 9 | 34 | Depth of invasion | | | | | | T0 | 1 | 0 | 1 | 0.734 | | T1 | 5 | 0 | 5 | | T2 | 3 | 1 | 2 | | T3 | 34 | 8 | 26 | | T4 | 21 | 5 | 16 | Stage | | | | | | 0 | 1 | 0 | 1 | 0.970 | | I | 7 | 1 | 6 | | II | 34 | 8 | 26 | | IIIa | 17 | 4 | 13 | | IIIb | 4 | 1 | 3 | | IV | 1 | 0 | 1 |
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