Short-Term Activation of Peroxisome Proliferator-Activated Receptors and Induces Tissue-Specific Effects on Lipid Metabolism and Fatty Acid Composition in Male Wistar Rats

Figure 5

Epididymal adipose tissue gene expression in Wistar rats after treatment with PPAR agonists for 12 days, normalized towards the control group. Red bars correspond to PPARα vs control and blue bars to PPARγ vs control. Acox1, fatty acyl-CoA oxidase 1; ANOVA, analysis of variance; Cd36, cluster of differentiation 36; Cpt1a, carnitine palmitoyltransferase 1a; Cpt2, carnitine palmitoyltransferase 2; Fabp4, fatty acid binding protein 4; Fas, fatty acid synthase; Fatp1, fatty acid transport protein 1; Hmgcs2, 3-hydroxy-3-methylglutaryl-CoA synthase 2; Lipe, hormone sensitive lipase E; Lpl, lipoprotein lipase; Pgc1α, peroxisome proliferator-activated receptor ɣ coactivator 1α; Pltp, phospholipid transfer protein; Pparα, peroxisome proliferator-activated receptor α; Pparɣ, peroxisome proliferator-activated receptor ɣ; TNFa, tumor necrosis factor alpha; Ucp2, Uncoupling protein 2.