|
Gene set name (# in Hallmark set) | Description | Overlap | value |
|
(a) Induced by Pio in WT mice on control diet |
OXIDATIVE_PHOSPHORYLATION [200] | Genes encoding proteins involved in oxidative phosphorylation. | 48 | 2.55-35 |
MYC_TARGETS_V1 [200] | A subgroup of genes regulated by MYC - version 1 (v1). | 40 | 2.33-26 |
ADIPOGENESIS [200] | Genes upregulated during adipocyte differentiation (adipogenesis). | 31 | 3.41-17 |
ESTROGEN_RESPONSE_LATE [200] | Genes defining late response to estrogen. | 24 | 5.47-11 |
FATTY_ACID_METABOLISM [158] | Genes encoding proteins involved in metabolism of fatty acids. | 21 | 1.34-10 |
MTORC1_SIGNALING [200] | Genes upregulated through activation of mTORC1 complex. | 23 | 2.45-10 |
GLYCOLYSIS [200] | Genes encoding proteins involved in glycolysis and gluconeogenesis. | 21 | 8.17-9 |
UNFOLDED_PROTEIN_RESPONSE [113] | Genes upregulated during unfolded protein response. | 16 | 8.78-9 |
ESTROGEN_RESPONSE_EARLY [200] | Genes defining early response to estrogen. | 19 | 2-7 |
DNA_REPAIR [150] | Genes involved in DNA repair. | 16 | 4.31-7 |
(b) Induced by Pio in WT mice on HFD |
OXIDATIVE_PHOSPHORYLATION [200] | Genes encoding proteins involved in oxidative phosphorylation. | 31 | 2.38-24 |
MYC_TARGETS_V1 [200] | A subgroup of genes regulated by MYC—version 1 (v1). | 25 | 1.66-17 |
ADIPOGENESIS [200] | Genes upregulated during adipocyte differentiation (adipogenesis). | 20 | 2.72-12 |
ESTROGEN_RESPONSE_LATE [200] | Genes defining late response to estrogen. | 15 | 1.22-7 |
(c, d) Suppressed by Pio in WT mice on control or HFD |
No overlaps found. | | | |
(e, f, g, h) Induced or suppressed by Pio or HFD in KO mice in presence or absence of HFD or Pio |
No overlaps found. | | | |
|