To Probe Full and Partial Activation of Human Peroxisome Proliferator-Activated Receptors by Pan-Agonist Chiglitazar Using Molecular Dynamics Simulations

<div>Root mean square fluctuations of chiglitazar from our MD simulation compared to the crystal ligand systems for PPAR<i>α</i> (a) (PDB ID: 3VI8), PPAR<i>β</i> (b) (PDB ID: 3TKM), and PPAR<i>γ</i> (c) (PDB ID: 2PRG) where the date for the crystal ligands are in blue and chiglitazar’s data is in black.</div>

PPAR Research

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Figure 8: To Probe Full and Partial Activation of Human Peroxisome Proliferator-Activated Receptors by Pan-Agonist Chiglitazar Using Molecular Dynamics Simulations 

Figure 8 | To Probe Full and Partial Activation of Human Peroxisome Proliferator-Activated Receptors by Pan-Agonist Chiglitazar Using Molecular Dynamics Simulations 