PPARG Drives Molecular Networks as an Inhibitor for the Pathologic Development and Progression of Lung Adenocarcinoma

Figure 1

Contradirectional common targets of PPARG and lung adenocarcinoma according to literature that was also tested using expression data. Entities in blue represent a decreased expression level from the mega-analysis using 13 LA datasets; entities in red represent an increased expression level. Entities highlighted in blue (genes at the bottom of the figure) were literature implicated with a downregulation in the case of LA; highlighted in red (genes at the top of the figure) means they were upregulated. The polarity of the relationships was denoted as “-|” for negative effects and “-+>” for positive effects.