Nitric Oxide Mediates Inflammation in Type II Diabetes Mellitus through the PPARγ/eNOS Signaling Pathway

Figure 3

The eNOS, NO, PPARγ, inflammatory factors levels in HepG2 cells. (a) The expression of eNOS in insulin-induced HepG2 cells. (b) The change of nitrite and nitrate in insulin-induced HepG2 cells treated with eNOS inhibitor or si-PPARγ. (c) The effect of PPARγ inhibition on the expression of eNOS, PPARγ, C-reactive protein, and heptoglobin expression in insulin-induced HepG2 cells. (d) The IL-1β, TNF-α, and IL-6 levels in insulin-induced HepG2 cells and insulin-induced HepG2 cells transfected with si-PPARγ.

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