Research Article
Apigenin Alleviates Liver Fibrosis by Inhibiting Hepatic Stellate Cell Activation and Autophagy via TGF-β1/Smad3 and p38/PPARα Pathways
Figure 2
Apigenin protects the liver against fibrosis induced by CCl4 and BDL in mice. Notes: (a, b) the levels of serum ALT and AST are presented as (; for CCl4 (BDL) group vs. control group; # for CCl4 (BDL)+apigenin (20 mg/kg) group vs. CCl4 (BDL) group; ! for CCl4 (BDL)+apigenin (40 mg/kg) group vs. CCl4 (BDL)+apigenin (20 mg/kg) group). (c, d) Representative H&E- and Masson-stained hepatic sections were examined under light microscopy and imaged at 200x and 100x magnifications.
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