Research Article
Fenofibrate Protects Cardiomyocytes from Hypoxia/Reperfusion- and High Glucose-Induced Detrimental Effects
Figure 10
Fenofibrate (10 μM) attenuates damage to the mitochondrial ultrastructure in primary cultures of cardiomyocytes subjected to hypoxia/reperfusion (H/R), high glucose (HG), and HG+H/R. Details of the ultrastructure by electron microscopy: 500 nm, 50,000x. (a) Control-DMSO and control/fenofibrate, (b) H/R-DMSO and H/R-fenofibrate, (c) HG-DMSO and HG-fenofibrate, and (d) HG+H/R-DMSO and HG+H/R-fenofibrate. The images are representative of 6 experiments per group.
(a) |
(b) |
(c) |
(d) |