Table of Contents
Pathology Research International
Volume 2010, Article ID 438534, 4 pages
Case Report

Mural Nodules of Clear Cell Carcinoma in a Mucinous Borderline Tumor of the Ovary: A Case Report

1Department of Anatomic Pathology, The Cleveland Clinic, Cleveland, OH 44195, USA
2Department of Obstetrics and Gynecology, The Cleveland Clinic, Cleveland, OH 44195, USA

Received 17 September 2009; Revised 4 January 2010; Accepted 28 January 2010

Academic Editor: I-Tien Yeh

Copyright © 2010 Daniela S. Allende et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Mural nodules of ovarian mucinous borderline tumors are rare. In this study, we report a case of mural nodules of clear cell carcinoma in an intestinal type mucinous borderline tumor of the ovary. The patient was a 54-years-old woman presented with back and pelvic pain for 3 months. A right-sided multiloculated ovarian mass approximately 20 cm was identified on the CT scan. CA-125 was moderately elevated. She underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy and bilateral pelvic and para-aortic lymphadenectomy. Grossly, the right ovarian mass showed a multiloculated cystic mass with mucinous fluid. There were papillations in the internal surface and two mural nodules were seen. Microscopic examination revealed that the cystic mass was an intestinal type borderline mucinous tumor. The mural nodules showed a classic histology of clear cell carcinoma with tubulocystic and papillary growth patterns. This is an extremely rare case of mural nodules of clear cell carcinoma arising in a mucinous borderline tumor.