Pathology Research International / 2011 / Article / Fig 4

Case Report

Prostatic Adenocarcinoma Metastatic to Pleomorphic Liposarcoma, a “Collision Phenomenon”: Report of a Case with Review of Pelvic Collision Tumors

Figure 4

Image Plate II. (a) Malignant prostatic acini are strongly positive for AE1/AE3. The spindle cells are negative. (Original magnification ×100.) (b) Strong expression of vimentin in the liposarcoma component. (Original magnification ×40.) (c) CD34 highlights the plexiform network of capillaries in the tumor. (Original magnification ×40.) (d) FISH analysis, dual-color break-apart probe for CHOP is positive for the translocation, represented by a cell with one yellow signal (normal), one red (part of CHOP gene), and one green signal (part of CHOP gene). (e) FISH analysis, amplification probe for MDM2, is negative (not amplified). (f) FISH analysis, dual-color fusion probes for TMPRSS (red) and ERG (green), is positive, represented by cells with at least one fused yellow signal (red + green).

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