Laminar Distribution of the Pathological Changes in Sporadic and Variant Creutzfeldt-Jakob Disease

Table 1

Demographic data and gross pathological features of the sporadic (sCJD) and variant Creutzfeldt-Jakob disease (vCJD) cases studied.

Case	Sex	Age at onset	Duration	Brain weight	Gross atrophy
		(years)	(years)	(gm)
sCJD
A	F	71	0.25	1222	Bilateral, diffuse
B	F	59	2.4	986	Severe Fr, T, C
C	F	71	0.16	1275	Mild Fr
D	F	71	0.25	1169	Mild
E	M	78	0.25	1562	Moderate
F	M	50	0.25	1292	None
G	M	67	0.16	1425	Moderate
H	F	69	0.16	1365	Mild
I	M	60	NA	1621	None
J	M	61	1	1270	Mild
K	F	78	0.40	1061	Mild, diffuse
vCJD
A	F	39	2	586 L	None
B	F	28	1	1375	None
C	F	28	1	NA	NA
D	M	19	1	NA	NA
E	M	30	1	699 R	None
F	M	48	2	1470	None
G	F	34	1	810 L	None
H	M	18	1	1434	None
I	M	24	1	NA	NA
J	F	21	2	1394	None
K	M	35	1	718 R	None

Abbreviations: M: Male, F: Female, Fr: Frontal cortex, T: temporal cortex, C: cerebellum, R: Right hemisphere, L: Left hemisphere, NA = data not available.