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Pathology Research International
Volume 2011 (2011), Article ID 306921, 3 pages
Case Report

Primary Small Cell Neuroendocrine Carcinoma of Vagina: A Rare Case Report

1Department of Pathology, GMERES Medical College Sola, B-37, Marutinandan Vihar Bungalows, Near Aarohi Villa, S.P. Ring Road, Bopal, Ahmedabad 380058, India
2Department of Pathology, C.U. Shah Medical College & Hospital, Surendranagar 363001, Gujarat, India

Received 1 February 2011; Revised 26 July 2011; Accepted 30 July 2011

Academic Editor: Helmut Denk

Copyright © 2011 Jignasa N. Bhalodia et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Primary small cell neuroendocrine carcinoma of vagina is an extremely rare disease. There have been only 26 previously reported cases in literature. Here, we report a case of primary small cell neuroendocrine carcinoma of vagina. Immunohistochemistry (IHC) showed tumor cells positive for synaptophysin, chromogranin, and neuron-specific enolase (NSE).