Genetic Polymorphism of Cancer Susceptibility Genes and HPV Infection in Cervical Carcinogenesis

Table 6

HPV status and frequency of MDM2-SNP309 in exfoliated cervical cell samples.

Study group	𝑛	Genotype at MDM2-SNP309		OR	95% CI	P value
		TT	TG + GG
High-risk HPV−
Normal	42	8 (18.2%)	36 (81.8%)	1
LSIL	74	14 (18.4%)	60 (81.1%)	0.95	0.36–2.49	.921
HSIL	11	4 (36.7%)	7(63.3%)	0.41	0.10–1.59	.186
High-risk HPV+
Normal	10	3 (30.0%)	7 (70.0%)	1
LSIL	28	12 (42.9%)	16 (57.1%)	0.38	0.10–1.42	.475
HSIL	30	3 (10.0%)	27 (90.0%)	8.88	2.34–33.63	.003

OR: odds ratio.
CI: confidence interval.