Research Article

Role of Apoptosis in Rabies Viral Encephalitis: A Comparative Study in Mice, Canine, and Human Brain with a Review of Literature

Figure 2

DNA laddering in Mouse brain. (a) DNA laddering (arrows) is seen only in suckling mouse brain infected with CVS strain of rabies virus (lanes 5 & 6). No laddering seen in street-virus-infected suckling mouse brain (lanes 3 & 4) and weanling adult mouse brain infected with street (lane 7) and CVS strain (lane 8) of rabies virus. (b) DNA laddering (arrows) in suckling mouse brain infected with CVS strain of rabies virus (lanes 3 & 8) and absence of laddering in street-virus-infected adult mouse brain infected with CVS and street strain of rabies virus. (c) DNA laddering (arrows) in suckling mouse brain infected with CVS strain of rabies virus and absence of laddering in street-virus-infected dog brain and human brain. (d) DNA laddering (arrows) in suckling mouse brain infected with CVS strain of rabies virus-time point study. DNA laddering exhibited only on the 6th day P.I.
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