Role of Apoptosis in Rabies Viral Encephalitis: A Comparative Study in Mice, Canine, and Human Brain with a Review of Literature

Table 1

Comparison of the incubation period (IP) and duration of illness (DOI) with different routes of inoculation and strains of rabies virus.

		Incubation period (IP) and duration of illness (DOI)
Type of Virus and Route of inoculation		Suckling mice (Age: 0–2 days)	Weanling mice (Age: 21 days)	Adult mice (Age: 3 months)
Street	Intracerebral
	IP	8–10 days	6–8 days	6–8 days
	DOI	24 hrs	24 hrs	24 hrs
CVS	Intracerebral
	IP	≤6 days	4–6 days	4–6 days
	DOI	48–72 hrs	48–72 hrs	48–72 hrs
Street	Intramuscular	Not done
	IP		20–25 days	20–25 days
	DOI		24 hrs	24 hrs
CVS	Intramuscular	Not Done
	IP		8–10 days	8–10 days
	DOI		48–72 hrs	48–72 hrs

Incubation period (IP): from bite to onset of clinical symptoms.
Duration of illness (DOI): from onset of clinical manifestation to death.