Fine-Needle Aspiration Biopsy of Hepatocellular Carcinoma and Related Hepatocellular Nodular Lesions in Cirrhosis: Controversies, Challenges, and Expectations
Figure 13
FNA of metastatic adrenocortical carcinoma to the liver. (a) Cohesive group of tumor cells with ample cytoplasm, central round nucleus, distinct nucleolus, and granular chromatin. (Giemsa, ×400). Inset: tumor cells contain fine lipid vacuoles in the cytoplasm (Giemsa, ×200). (b) Loosely cohesive tumor cells with nuclear features mimicking malignant hepatocytes (Papanicolaou, ×400). (c) Histology of adrenal tumor shows trabecular-sinusoidal pattern and polygonal cells with central round nucleus and nucleolus, mimicking HCC. The cytoplasm shows eosinophilic granularity (H&E, ×200).
