Review Article

Gastrointestinal Mesenchymal Neoplasms other than Gastrointestinal Stromal Tumors: Focusing on Their Molecular Aspects

Figure 6

Schematic of platelet-derived growth factor receptor- (PDGFR-)related signaling pathways. Mutations can lead to activation of PDGFR independent of ligand binding. Numerous downstream pathways may lead to neoplastic advantages such as cell proliferation, growth, and survival.
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