Clinical Study

Immunoreactivity of the 14F7 Mab (Raised against N-Glycolyl GM3 Ganglioside) as a Positive Prognostic Factor in Non-Small-Cell Lung Cancer

Table 6

Relation between S-phase fraction and mitotic index with the 14F7 Mab immunoreactivity in diploid non-small-cell lung carcinoma.

Proliferation rates14F7 Mab reactivity
NegativeWeakModerateIntenseSpearman correlation
No. (%)No. (%)No. (%)No. (%) value

S-phase fraction (SPF)0.02080.5126
 0–5
 6–253 (27.3)
 26–506 (54.5)
 >502 (18.2)
Total03 (27.3)6 (54.5)2 (18.2)
Mitotic index0.0284−0.4143
 No evident2 (7.1)
 Low1 (3.6)2 (7.1)6 (21.4)
 Moderate1 (3.6)2 (7.1)7 (25.0)3 (10.7)
 High1 (3.6)2 (7.1)1 (3.6)
Total2 (7.1)3 (10.7)11 (39.3)12 (42.8)

No. Number of cases, % percentages, value using Spearman correlation test, s Spearman correlation coefficient.