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Pathology Research International
Volume 2012 (2012), Article ID 690390, 9 pages
http://dx.doi.org/10.1155/2012/690390
Review Article

Clinical and Pathological Manifestations with Differential Diagnosis in Behçet's Disease

Department of Dermatology, Faculty of Medicine, Mersin University, Zeytinlibahçe 33079, Mersin, Turkey

Received 26 August 2011; Accepted 13 October 2011

Academic Editor: Ümit Tursen

Copyright © 2012 Aysin Kokturk. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Behçet's disease is a multisystemic inflammatory disease of unknown etiology which usually occurs as a trait of symptoms: aphthous stomatitis, genital ulcerations, and ocular disease. At the beginning of the disease the diagnosis is uncertain because of various clinical manifestations and a long period up to the full clinical picture manifestation. Since neither the laboratory data nor the histopathological signs are truly pathognomonic in Behçet's disease, the differential diagnosis depends on a careful evaluation of the medical history and meticulous physical examination to detect concomitant systemic manifestations. Sometimes, some laboratory test may help establish the diagnosis. Subspecialty referral to ophthalmology, rheumatology, neurology, and gastroenterology should be considered when indicated.