Comparative Study of Cytomorphological Robinson’s Grading for Breast Carcinoma with Modified Bloom-Richardson Histopathological Grading
Figure 1
(a) Loosely cohesive cluster of mild pleomorphic ductal cells with smooth nuclear membrane and indistinct nucleoli—cytologic grade I (Giemsa ×400). (b) Invasive breast carcinoma with tubular/glandular differentiation, little increase in size, regular outlines, and uniform nuclear chromatin—histological grade I (H&E ×100, inset, H&E ×400). (c) Loosely cohesive cluster as well as single cells with moderate pleomorphism, slightly irregular nuclear membrane, and noticeable nucleoli. Nuclei are three to four times the erythrocytes—cytologic grade II (Giemsa ×400) (inset, H&E ×1000). (d) Invasive breast carcinoma with cords, islands with tubular differentiation, moderate variability in size and shape, open vesicular nuclei, and visible nucleoli—histological grade II (H&E ×100, inset, H&E ×400).
