Table of Contents Author Guidelines Submit a Manuscript
Pathology Research International
Volume 2013, Article ID 828214, 3 pages
http://dx.doi.org/10.1155/2013/828214
Research Article

A Comparison of Hemoglobin Levels in Untreated and Treated Groups of HIV Patients on ART Including Zidovudine

1Department of Pathology, D.D.U. Hospital, Hari Nagar, New Delhi 110066, India
2Department of Pathology, Maulana Azad Medical College, New Delhi 110002, India

Received 9 October 2013; Revised 15 December 2013; Accepted 16 December 2013

Academic Editor: Piero Tosi

Copyright © 2013 Jitendra Singh Nigam et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. B. J. Bain, Haemoglobinopathy Diagnosis, Blackwell Publishing, Malden, Mass, USA, 2nd edition, 2006.
  2. J. Howard, J. S. Henthorn, S. Murphy, and S. C. Davies, “Implications of increased haemoglobin A2 values in HIV positive women in the antenatal clinic,” Journal of Clinical Pathology, vol. 58, no. 5, pp. 556–558, 2005. View at Publisher · View at Google Scholar · View at Scopus
  3. M. Spiga, D. A. Weidner, C. Trentesaux, R. D. Leboeuf, and J. Sommadossi, “Inhibition of β-globin gene expression by 3′-azido-3′-deoxythymidine in human erythroid progenitor cells,” Antiviral Research, vol. 44, no. 3, pp. 167–177, 1999. View at Publisher · View at Google Scholar · View at Scopus
  4. M. J. Wilkinson, B. J. Bain, L. Phelan, and A. Benzie, “Increased haemoglobin A2 percentage in HIV infection: disease or treatment?” AIDS, vol. 21, no. 9, pp. 1207–1208, 2007. View at Publisher · View at Google Scholar · View at Scopus
  5. J.-P. Routy, M. Monte, R. Beaulieu, E. Toma, L. St-Pierre, and M. Dumont, “Increase of hemoglobin A2 in human immunodeficiency virus-1-infected patients treated with zidovudine,” American Journal of Hematology, vol. 43, no. 2, pp. 86–90, 1993. View at Google Scholar · View at Scopus
  6. F. Galacteros, F. Amaudric, C. Prehu et al., “Acquired unbalanced hemoglobin chain synthesis during HIV infection,” Comptes Rendus de l'Academie des Sciences. Series III, vol. 316, no. 4, pp. 437–440, 1993. View at Google Scholar · View at Scopus
  7. A. C. Gorakshakar and R. B. Colah, “Cascade screening for β-thalassemia: a practical approach for identifying and counseling carriers in India,” Indian Journal of Community Medicine, vol. 34, no. 4, pp. 354–356, 2009. View at Publisher · View at Google Scholar · View at Scopus
  8. S. Rao, R. Kar, S. K. Gupta, A. Chopra, and R. Saxena, “Spectrum of haemoglobinopathies diagnosed by cation exchange-HPLC & modulating effects of nutritional deficiency anaemias from north India,” Indian Journal of Medical Research, vol. 132, no. 11, pp. 513–519, 2010. View at Google Scholar · View at Scopus
  9. G. Moyle, W. Sawyer, M. Law, J. Amin, and A. Hill, “Changes in hematologic parameters and efficacy of thymidine analogue-based, highly active antiretroviral therapy: a meta-analysis of six prospective, randomized, comparative studies,” Clinical Therapeutics, vol. 26, no. 1, pp. 92–97, 2004. View at Publisher · View at Google Scholar · View at Scopus
  10. M. H. Steinberg and J. G. Adams III, “Hemoglobin A2: origin, evolution, and aftermath,” Blood, vol. 78, no. 9, pp. 2165–2177, 1991. View at Google Scholar · View at Scopus
  11. S. Pornprasert, P. Leechanachai, V. Klinbuayaem et al., “Effect of haematological alterations on thalassaemia investigation in HIV-1-infected Thai patients receiving antiretroviral therapy,” HIV Medicine, vol. 9, no. 8, pp. 660–666, 2008. View at Publisher · View at Google Scholar · View at Scopus
  12. P. Kosalaraksa, S. Wiangnon, T. Bunupuradah et al., “High HbA2 due to zidovudine exposure: implication for β-thalassemia trait screening,” in Proceedings of the 19th International AIDS Conference, Abstract no. MOPE045.
  13. S. Pornprasert, K. Sukunthamala, P. Leechanachai, and T. Sanguansermsri, “Increased Hb A2 values in an HIV-1-infected patient receiving antiretroviral drugs: a pitfall for thalassemia antenatal diagnosis,” Hemoglobin, vol. 33, no. 2, pp. 158–161, 2009. View at Publisher · View at Google Scholar · View at Scopus
  14. G. Stamatoyannopoulos, C. A. Blau, B. Nakamoto et al., “Fetal hemoglobin induction by acetate, a product of butyrate catabolism,” Blood, vol. 84, no. 9, pp. 3198–3204, 1994. View at Google Scholar · View at Scopus
  15. A. F. Collins, N. L. C. Luban, and G. J. Dover, “Increased fetal hemoglobin production in patients receiving valproic acid for epilepsy,” Blood, vol. 84, no. 5, pp. 1690–1691, 1994. View at Google Scholar · View at Scopus
  16. B. P. Alter and H. S. Gilbert, “The effect of hydroxyurea on hemoglobin F in patients with myeloproliferative syndromes,” Blood, vol. 66, no. 2, pp. 373–379, 1985. View at Google Scholar · View at Scopus