Matrix Metalloproteinases 2 and 9 Immunoexpression in Prostate Carcinoma at the Positive Margin of Radical Prostatectomy Specimens
Figure 3
(a) Glands lined with hyperplastic epithelium and PIN (hematoxylin and eosin staining, 100x). (b) MMP-2 and MMP-9 immunohistochemistry indicates weak or negative expression in hyperplastic epithelium, except for the PIN, where the expression is strong (100x). (c) MMP-9 immunoexpression in moderately differentiated prostate cancer. Note the intense staining in the cytoplasm of tumor cells and the strongly positive reaction in the cytoplasm of stromal cells (200x). (d) MMP-2 immunoexpression in poorly differentiated prostate cancer. Note the strong cytoplasmic staining intensity (200x).
